Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Markov chain description of the stepwise mutation model: local and global behaviour of the allele process.

Journal of theoretical biology - 21 Sept 2010

Caliebe Amke, Jochens Arne, Krawczak Michael, Rösler Uwe

Abstract excerpt

The stepwise mutation model (SMM) is a simple, widely used model to describe the evolutionary behaviour of microsatellites. We apply a Markov chain description of the SMM and derive the marginal and joint properties of this process. In addition to the standard SMM, we also consider the normalised allele process. In contrast to the standard process, the normalised process converges to a stationary distribution. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Computer Simulation
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Markov Chains

Share to Microsatellite Repeats

Share to Models, Genetic

Share to Mutation

Source

Identifiers

PMID: 20600139
DOI: 10.1016/j.jtbi.2010.06.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Markov chain description of the stepwise mutation model: local and global behaviour of the allele process.PMID 20600139Read ↗

Estimating effective population size or mutation rate with microsatellites.Semantic proximity Read ↗

Simultaneous estimation of all the parameters of a stepwise mutation model.Semantic proximity Read ↗

Statistical Inference in the Wright-Fisher Model Using Allele Frequency Data.Semantic proximity Read ↗

Statistical properties of population differentiation estimators under stepwise mutation in a finite island model.Semantic proximity Read ↗

The multivariate Wright-Fisher process with mutation: Moment-based analysis and inference using a hierarchical Beta model.Semantic proximity Read ↗

The mutation process of microsatellites during the polymerase chain reaction.Semantic proximity Read ↗

Microsatellite evolution: Markov transition functions for a suite of models.Semantic proximity Read ↗

VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach.Semantic proximity Read ↗

Allele frequencies at microsatellite loci: the stepwise mutation model revisited.Semantic proximity Read ↗

Fast and accurate estimation of the population-scaled mutation rate, theta, from microsatellite genotype data.Semantic proximity Read ↗

Inference from the stationary distribution of allele frequencies in a family of Wright-Fisher models with two levels of genetic variability.Semantic proximity Read ↗

Genetic drift in populations governed by a Galton-Watson branching process.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.