Article
Molecular analysis of an acatalasemic mouse mutant.
Biochemical and biophysical research communications - 31 Dec 1990
Shaffer J B, Preston K E
Abstract excerpt
The Csb acatalasemia mouse mutant differentially expresses reduced levels of catalase activity in a tissue specific manner. In order to pinpoint the molecular lesion that imparts the acatalasemia phenotype in Csb mice we have utilized the polymerase chain reaction technique to isolate catalase cD...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Catalase
- DNA
- Gene Expression Regulation
- Humans
- Kidney
- Liver
- Mice
- Mice, Inbred C3H
- Mice, Mutant Strains
- Molecular Sequence Data
- Mutation
- Phenotype
- Polymerase Chain Reaction
- RNA, Messenger
- Sequence Homology, Nucleic Acid