Article
Relationship between catalase activity, life span and some parameters associated with antioxidant defenses in Drosophila melanogaster.
Mechanisms of ageing and development - 1 May 1992
Orr W C, Arnold L A, Sohal R S
Abstract excerpt
This study was conducted on Drosophila melanogaster mutants with different levels of catalase activity in order to assess the role of antioxidant defenses in the aging process. We present here the analysis of two mutant strains: the catn1/catn4 heterozygote which exhibits no detectable catalase activity and the catn2 homozygote which exhibits approximately 14% that of the parent reference strain. Since insects...
Topics
- Aging
- Animals
- Antioxidants
- Catalase
- Drosophila melanogaster
- Glutamate-Cysteine Ligase
- Glutathione
- Glutathione Reductase
- Longevity
- Male
- Mutation
