Article
Lack of HIV-1 V3 region sequence diversity in two haemophiliac patients infected with a putative biologic clone of HIV-1.
AIDS (London, England) - 1 Oct 1991
Cichutek K, Norley S, Linde R, Kreuz W, Gahr M, Löwer J, von Wangenheim G, Kurth R
Abstract excerpt
Peripheral blood mononuclear cells (PBMC) from two haemophilia B patients, who presumably became infected with a putative HIV-1 biological clone following treatment with the same suspected batch of commercial factor, were used to clone and sequence the hypervariable V3 region of the HIV-1 envelope protein. In 10 of 12 clones the V3 region was identical and two (one from each patient) had a single non-synonymous...
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