Hb Saint Nazaire (beta 103[G5]Phe-->Ile): a new example of polycythemia due to a hemoglobin variant with increased oxygen affinity.

doi:10.1002/ajh.2830440105

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Article

Hb Saint Nazaire (beta 103[G5]Phe-->Ile): a new example of polycythemia due to a hemoglobin variant with increased oxygen affinity.

American journal of hematology - 1 Sept 1993

Wajcman H, Kister J, M'Rad A, Promé D, Milpied N, Rapp M J, Harousseau J L, Riou J, Bardakdjian J, Galacteros F

Abstract excerpt

Hb Saint Nazaire [beta 103 (G5) Phe-->Ile] was found in four apparently unrelated French families. The five patients carrying this hemoglobin have been detected because of a moderate erythrocytosis. The structural abnormality of Hb Saint Nazaire concerns the same residue as in Hb Heathrow [beta 1...

Topics

Adolescent
Adult
Aged
Amino Acids
Chromatography, High Pressure Liquid
Genetic Variation
Heme
Hemoglobins, Abnormal
Humans
Isoleucine
Leucine
Male
Mass Spectrometry
Middle Aged
Oxygen
Phenylalanine
Polycythemia

Source

Open in PubMed

Identifiers

PMID: 8342560
DOI: 10.1002/ajh.2830440105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8342560-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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