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Article

Hb Calais [beta76(E20)Ala --> Pro]: a family study of a variant with decreased oxygen affinity.

Hemoglobin - 1 Jan 2006

Bardet Valérie, Adam Mircea, Yvart Jeanine, Wajcman Henri, Galacteros Frédéric, Favier Rémi

Abstract excerpt

Secondary to the detection of a chronic anemia with a slightly increased Hb F level in a 7-year-old boy carrying a hemoglobin (Hb) variant, we investigated the members of his family and found that they were related to the original case of Hb Calais. In the present study, we report the clinical and biological impacts of this Hb variant in various members of three generations of this family.

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Source

Identifiers

PMID: 16540413
DOI: 10.1080/03630260500454014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hb Calais [beta76(E20)Ala --> Pro]: a family study of a variant with decreased oxygen affinity.PMID 16540413Read ↗

Hemoglobin Calais [beta 76 (E20) Ala----Pro]: a hemoglobin variant with decreased intrinsic oxygen affinity.Semantic proximity Read ↗

A novel beta-globin variant: Hb Poços de Caldas [beta 61(E5)Lys-->Gln].Semantic proximity Read ↗

Novel, de novo, beta-globin variant with decreased oxygen affinity (HBB:c.317T>A, "Hemoglobin St. George") in a healthy child with low oxygen saturations and anemia.Semantic proximity Read ↗

Hb Camperdown [alpha 2 beta 2 104(G6)Arg-->Ser] identified by DNA analysis in a Brazilian family.Semantic proximity Read ↗

Description of Three New α Variants and Four New β Variants: Hb Montluel [α110(G17)Ala → Val; HBA1: c.332C > T], Hb Cap d'Agde [α131(H14)Ser → Cys; HBA2: c.395C > G] and Hb Corsica [α100(G7)Leu → Pro; HBA1: 302T > C]; Hb Nîmes [β104(G6)Arg → Gly; HBB: c.313A > G], Hb Saint Marcellin [β112(G14)Cys → Gly; HBB: c.337T > G], Hb Saint Chamond [β80(EF4)Asn → 0; HBB: c.241_243delAAC] and Hb Dompierre [β29(B11)Gly → Arg; HBB: c.88G > C].Semantic proximity Read ↗

Hb Limassol [beta8(A5)Lys-->Asn]: a new hemoglobin variant.Semantic proximity Read ↗

Identification of a new hemoglobin variant: Hb St. Joseph's [beta77(EF1)His-->Leu].Semantic proximity Read ↗

Four new beta chain hemoglobin variants without clinical or hematological effects: Hb San Bruno [beta39(C5)Gln-->His]; Hb Fort Dodge [beta93(F9)Cys-Tyr]; Hb Rhode Island [beta116(G18)His-->Tyr]; and Hb Inglewood [beta142(H20)Ala-->Thr].Semantic proximity Read ↗

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Hb Campinas [alpha26(B7)Ala -->Val]: a novel, electrophoretically silent, variant.Semantic proximity Read ↗

A new unstable alpha2-globin gene variant: Hb Chartres [alpha33(B14)Phe --> Ser].Semantic proximity Read ↗

Hb Vila Real [beta36(C2)Pro-->His]: a newly discovered high oxygen affinity variant.Semantic proximity Read ↗

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