Article
Inv1: an Edwardsiella tarda invasin and a protective immunogen that is required for host infection.
Fish & shellfish immunology - 1 Apr 2012
Li Mo-fei, Hu Yong-hua, Zheng Wen-jiang, Sun Bo-guang, Wang Chun-lin, Sun Li
Abstract excerpt
Invasin is an outer membrane protein that is known to mediate entry of enteric bacteria into mammalian cells. In this study, we analyzed the function and immunoprotective potential of the invasin Inv1 from Edwardsiella tarda, a serious fish pathogen that can also infect humans. In silico analysis indicated that Inv1 possesses a conserved N-terminal DUF3442 domain and a C-terminal group 1 bacterial Ig-like domain....
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