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Article

Cytotoxic T-cell response and in vivo protection against tumor cells harboring activated ras proto-oncogenes.

Journal of the National Cancer Institute - 18 Aug 1993

Fenton R G, Taub D D, Kwak L W, Smith M R, Longo D L

Abstract excerpt

BACKGROUND: Activated forms of the ras proto-oncogene have been found in approximately 30% of human malignancies, including pancreatic, colon, and lung adenocarcinomas. Ras oncoproteins arise by somatic mutation and contain amino acid changes at residues 12, 13, or 61, thus generating unique tumor-specific proteins that are attractive targets for cancer therapy. PURPOSE: The goal of this study was to determine...

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PMID: 8340941
DOI: 10.1093/jnci/85.16.1294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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