Article
[Familial lupus erythematosus with partial C4 deficiency].
Wiener klinische Wochenschrift - 1 Jan 1993
Ploier R, Tappeiner G, Spaeth P, Emhofer J
Abstract excerpt
A report is presented of a family with selective partial C4-deficiency in 3 members, two of whom suffer from systemic lupus erythematosus (SLE). C4-allotyping showed the presence of one "silent gene" for the C4B-locus (C4BQO) in these three cases. Presumably it is not the reduced C4-content per se that plays the essential role in the pathogenesis of familial SLE, but the combination of the C4BQO-allele with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.