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Article

Clinical implications of the apolipoprotein E polymorphism and genetic variants: current methods for apo E phenotyping.

Annales de biologie clinique - 1 Jan 1991

Steinmetz A

Abstract excerpt

There is agreement about the influence of the genetic apolipoprotein (apo E) polymorphism on plasma lipid and apoprotein levels in man. Whereas the association of the apo E2 isoform with primary dysbetalipoproteinemia and hyperlipoproteinemia type III is well established, the plasma- and LDL-cholesterol lowering effects of apo E2 and the phenomenon of apo E4 raising these parameters on the development of coronary...

Topics

Apolipoproteins E
Coronary Disease
Humans
Hyperlipidemias
Hyperlipoproteinemia Type III
Isoelectric Focusing
Phenotype
Polymorphism, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2048769

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2048769-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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