Article
Apolipoprotein E allele frequencies in an Italian population: relation to age and lipid profile.
Aging (Milan, Italy) - 1 Aug 1995
Ruiu G, Cassader M, Gambino R, Alemanno N, Demichieli F, Pagano A, Veglia F, Pagano G
Abstract excerpt
Apo E phenotype and plasma Tg, Chol, LDL-Chol, HDL-Chol and Apo B levels were determined in a sample of 228 healthy Italian subjects (124 men and 104 women) aged 18-93. The allele frequencies were: epsilon 2 = 0.070; epsilon 3 = 0.829; epsilon 4 = 0.101 (among the lowest values in the literature). Division of the sample into four age groups indicated that epsilon 4 frequency decreased with age to 0 in persons...
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