Article
Strong association between the GSTM1-null genotype and lung cancer in a Turkish population.
Cancer genetics and cytogenetics - 15 Oct 2003
Pinarbasi Hatice, Silig Yavuz, Cetinkaya Oge, Seyfikli Zehra, Pinarbasi Ergun
Abstract excerpt
Glutathione S-transferases are possibly related to the detoxification of many xenobiotics involved in the etiology of cancer. To investigate the role of the glutathione S-transferase M1 deletion (GSTM1-null) in lung cancer, the polymerase chain reaction was used to determine the GSTM1 genotypes of lung cancer patients (n=101) and hospital (n=206) in a Turkish population. The prevalence of the GSTM1-null genotype...
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