Article
Anonymous marker loci within 400 kb of HLA-A generate haplotypes in linkage disequilibrium with the hemochromatosis gene (HFE)
American journal of human genetics - 1 Feb 1994
Yaouanq J, Perichon M, Chorney M, Pontarotti P, Le Treut A, el Kahloun A, Mauvieux V, Blayau M, Jouanolle A M, Chauvel B
Abstract excerpt
The hemochromatosis gene (HFE) maps to 6p21.3 and is less than 1 cM from the HLA class I genes; however, the precise physical location of the gene has remained elusive and controversial. The unambiguous identification of a crossover event within hemochromatosis families is very difficult; it is p...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 6
- Female
- Genetic Markers
- HLA-A Antigens
- Haplotypes
- Hemochromatosis
- Humans
- Linkage Disequilibrium
- Male