Pleiotropic models of polygenic variation, stabilizing selection, and epistasis.

doi:10.1093/genetics/134.2.609

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Article

Pleiotropic models of polygenic variation, stabilizing selection, and epistasis.

Genetics - 1 Jun 1993

Gavrilets S, de Jong G

Abstract excerpt

We show that in polymorphic populations many polygenic traits pleiotropically related to fitness are expected to be under apparent "stabilizing selection" independently of the real selection acting on the population. This occurs, for example, if the genetic system is at a stable polymorphic equil...

Topics

Alleles
Epistasis, Genetic
Gene Frequency
Genetic Variation
Mathematics
Models, Genetic
Polymorphism, Genetic
Selection, Genetic

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