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Article

Pleiotropic models of polygenic variation, stabilizing selection, and epistasis.

Genetics - 1 Jun 1993

Gavrilets S, de Jong G

Abstract excerpt

We show that in polymorphic populations many polygenic traits pleiotropically related to fitness are expected to be under apparent "stabilizing selection" independently of the real selection acting on the population. This occurs, for example, if the genetic system is at a stable polymorphic equilibrium determined by selection and the nonadditive contributions of the loci to the trait value either are absent, or...

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Identifiers

PMID: 8325491
DOI: 10.1093/genetics/134.2.609
PMCID: PMC1205502

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