Article
Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative variation.
Genetics - 1 Oct 1992
Kondrashov A S, Turelli M
Abstract excerpt
Apparent stabilizing selection on a quantitative trait that is not causally connected to fitness can result from the pleiotropic effects of unconditionally deleterious mutations, because as N. Barton noted, "...individuals with extreme values of the trait will tend to carry more deleterious alleles...." We use a simple model to investigate the dependence of this apparent selection on the genomic deleterious...
Topics
- Alleles
- Environment
- Genetic Variation
- Models, Genetic
- Mutation
- Selection, Genetic