Article
Stability and response of polygenic traits to stabilizing selection and mutation.
Genetics - 1 Jun 2014
de Vladar Harold P, Barton Nick
Abstract excerpt
When polygenic traits are under stabilizing selection, many different combinations of alleles allow close adaptation to the optimum. If alleles have equal effects, all combinations that result in the same deviation from the optimum are equivalent. Furthermore, the genetic variance that is maintained by mutation-selection balance is [Formula: see text] per locus, where μ is the mutation rate and S the strength of...
Topics
- Alleles
- Gene Frequency
- Genetic Fitness
- Models, Genetic
- Multifactorial Inheritance
- Mutation
- Selection, Genetic