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Article

Parental allele specific methylation of the human insulin-like growth factor II gene and Beckwith-Wiedemann syndrome.

Journal of medical genetics - 1 May 1993

Schneid H, Seurin D, Vazquez M P, Gourmelen M, Cabrol S, Le Bouc Y

Abstract excerpt

In an attempt to elucidate the role of methylation in parental imprinting at the IGF-II gene locus, for which imprinting has already been described in the mouse, we undertook an allele specific methylation study of the human IGF-II gene (mapped to 11p15.5) in a control population and in patients with Beckwith-Wiedemann syndrome. In control leucocyte DNA (16 unrelated adults and eight families), the maternal...

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Identifiers

PMID: 8320696
DOI: 10.1136/jmg.30.5.353
PMCID: PMC1016368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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