Article
Allelic methylation of H19 and IGF2 in the Beckwith-Wiedemann syndrome.
Human molecular genetics - 1 Aug 1994
Reik W, Brown K W, Slatter R E, Sartori P, Elliott M, Maher E R
Abstract excerpt
Beckwith-Wiedemann syndrome (BWS) is a congenital overgrowth syndrome with associated embryonal tumours. Most BWS cases are sporadic but familial cases occur in 15% of patients and in these there is linkage to chromosome 11p15. In addition, a small number of patients have cytogenetic abnormalitie...
Topics
- Alleles
- Beckwith-Wiedemann Syndrome
- Chromosomes, Human, Pair 11
- DNA
- Humans
- Methylation
- Polymerase Chain Reaction
- Restriction Mapping