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Article

Beckwith-Wiedemann syndrome demonstrates a role for epigenetic control of normal development.

Human molecular genetics - 1 Apr 2003

Weksberg Rosanna, Smith Adam C, Squire Jeremy, Sadowski Paul

Abstract excerpt

The Beckwith-Wiedemann syndrome (BWS) is characterized by somatic overgrowth and a predisposition to pediatric embryonal tumors. It is associated with genetic or epigenetic abnormalities in a cluster of imprinted genes found within a genomic region of approximately one megabase on human chromosome 11p15. Imprinted genes are expressed preferentially or exclusively from either the paternal or maternal allele. The...

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Source

Identifiers

PMID: 12668598
DOI: 10.1093/hmg/ddg067

Genes

IGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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