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Article

In vivo mutations in human blood cells: biomarkers for molecular epidemiology.

Environmental health perspectives - 1 Mar 1993

Albertini R J, Nicklas J A, Fuscoe J C, Skopek T R, Branda R F, O'Neill J P

Abstract excerpt

Mutations arising in vivo in recorder genes of human blood cells provide biomarkers for molecular epidemiology by serving as surrogates for cancer-causing genetic changes. Current markers include mutations of the glycophorin-A (GPA) or hemoglobin (Hb) genes, measured in red blood cells, or mutations of the hypoxanthine-guanine phosphoribosyltransferase (hprt) or HLA genes, measured in T-lymphocytes. Mean mutant...

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Identifiers

PMID: 8319611
DOI: 10.1289/ehp.9399135
PMCID: PMC1567038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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