Article
Identification of suppressin-producing cells in the rat pituitary.
Endocrinology - 1 Jul 1993
Ban E M, Propst S M, Blalock J E, LeBoeuf R D
Abstract excerpt
Suppressin (SPN) is a novel polypeptide that is synthesized and secreted by normal rat pituitary cells and a rat pituitary tumor cell line, GH3. Specifically, SPN is a negative regulator of growth that inhibits lymphoid and neuroendocrine cell proliferation. The objective of the present study was...
Topics
- Animals
- Antibodies, Monoclonal
- Cell Count
- Fluorescent Antibody Technique
- Hemolytic Plaque Technique
- Male
- Phenotype
- Pituitary Gland
- Pituitary Gland, Anterior
- Prolactin
- Rats
- Thymus Hormones