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Article

Identification of suppressin-producing cells in the rat pituitary.

Endocrinology - 1 Jul 1993

Ban E M, Propst S M, Blalock J E, LeBoeuf R D

Abstract excerpt

Suppressin (SPN) is a novel polypeptide that is synthesized and secreted by normal rat pituitary cells and a rat pituitary tumor cell line, GH3. Specifically, SPN is a negative regulator of growth that inhibits lymphoid and neuroendocrine cell proliferation. The objective of the present study was to identify the cells in the normal rat pituitary that produce SPN. A double immunofluorescence technique, using...

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Source

Identifiers

PMID: 8319573
DOI: 10.1210/endo.133.1.8319573

Genes

SPN
PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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