Article
A human pituitary tumor-derived folliculostellate cell line.
The Journal of clinical endocrinology and metabolism - 1 Mar 2000
Danila D C, Zhang X, Zhou Y, Dickersin G R, Fletcher J A, Hedley-Whyte E T, Selig M K, Johnson S R, Klibanski A
Abstract excerpt
Pituitary cells have been used for the study of hormone synthesis, secretion, and regulation. However, the lack of human cell lines of pituitary origin has made such studies in humans very difficult. Activin, a member of the transforming growth factor-beta cytokine family, is secreted by the pituitary and serves, in addition to regulating hormone biosynthesis, as a regulator of cell growth and differentiation. In...
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