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Article

Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype.

Endocrinology - 1 Jul 1994

Missale C, Boroni F, Sigala S, Zanellato A, Dal Toso R, Balsari A, Spano P

Abstract excerpt

GH-3 is an established cell line which, for the production of both PRL and GH, may be related to the bipotential somatomammotroph from which both somatotroph and mammotroph cells derive. In the present study we first report that GH-3 cells express both the gp140trk and the gp75 components of the nerve growth factor (NGF) receptor and that NGF dictates a nonneuronal type of differentiation of this cell line of...

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Source

Identifiers

PMID: 8013363
DOI: 10.1210/endo.135.1.8013363

Genes

NGF
PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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