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Article

Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis.

Trends in endocrinology and metabolism: TEM - 1 Sept 2002

Frohman Lawrence A, Kineman Rhonda D

Abstract excerpt

Growth hormone-releasing hormone (GHRH) is essential for expansion of the somatotrope lineage during pituitary development, and excessive GHRH secretion and/or action results in unregulated somatotrope proliferation and neoplastic transformation. Our understanding of the molecular and morphological bases for these effects from both animal and clinical studies has greatly increased during the past decade. However,...

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Source

Identifiers

PMID: 12163232
DOI: 10.1016/s1043-2760(02)00613-6

Genes

GHRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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