Dynamic fluctuations in the secretory activity of individual lactotropes as demonstrated by a modified sequential plaque assay.

Abstract excerpt

The existence of differences in the amount of hormone released by individual lactotropes from the same pituitary gland has been unequivocally established. Such secretory heterogeneity could reflect the existence of lactotrope subtypes that differ quantitatively in their capacity to release constant amounts of hormone over time. Alternatively, the same pattern could arise from the intermittent secretion of hormone...

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