Article
Genetic analysis of Alzheimer's disease: a summary of contributions to GAW8.
Genetic epidemiology - 1 Jan 1993
Wijsman E M
Abstract excerpt
Participants in the Alzheimer's disease component of GAW8 had access to three collections of pedigrees, complete with marker data from chromosomes 19 and 21. There were a total of 94 independent pedigrees and more than 2,000 individuals. Onset of the disorder varied widely among pedigrees. These data are briefly summarized along with a discussion of the problems associated with performing genetic analyses of...
Topics
- Alzheimer Disease
- Chromosome Aberrations
- Chromosome Disorders
- Chromosome Mapping
- Chromosomes, Human, Pair 19
- Chromosomes, Human, Pair 21
- Genetic Linkage
- Genetic Markers
- Genetic Variation
- Humans
- Lod Score
- Pedigree
- Phenotype
