Article
[Analysis of the amino acid changes of the hemagglutinin of H5 avian influenza virus].
Bing du xue bao = Chinese journal of virology - 1 Jan 2008
Xiu Wen-Qiong, Nakajima Katsuhisa, Nobusawa Eri
Abstract excerpt
We introduced 38 single-point amino acid changes into the hemagglutinin (HA) protein of the reassortmented A/Duck/Mongolia/54/01 (H5N2) strain by a PCR random mutation method. The percentage of amino acid changes on the HA domain that did not abrogate hemadsorption activity was calculated to be 89%. Changes in the amino acids of the HA2 domain were observed to be about half of those in the HA1 domain of these...
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