Article
[Genetic variation and recombination have profound medical implications].
Bulletin et memoires de l'Academie royale de medecine de Belgique - 1 Jan 2007
Thiry E, Alvarez M M L, Colombo M, Foidart J M
Abstract excerpt
In the family Herpesviridae, the subfamily Alphaherpesvirinae contains numerous pathogenic viruses, i.e. herpes simplex and varicella-zoster viruses. These double-stranded DNA viruses exhibit a complex cycle combining lytic and latent infections. Moreover, both intranuclear replication and a sophisticated DNA replication machinery allow an efficient proof-reading mechanism of correction. A low mutation rate is...
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