Article
A new deletional alpha-thalassemia detected in Yemenites with hemoglobin H disease.
American journal of hematology - 1 Mar 1994
Shalmon L, Kirschmann C, Zaizov R
Abstract excerpt
A new large deletion from the human alpha-globin gene cluster is characterized. It involves at least 39 kb and includes the two alpha-globin genes, the theta 1-gene, all the pseudogenes, and the two hypervariable regions (HVRs), interzeta-HVR and alpha-globin 3'HVR. The conserved zeta-globin gene...
Topics
- Autoradiography
- DNA Restriction Enzymes
- Female
- Gene Deletion
- Genotype
- Humans
- Israel
- Jews
- Male
- Phenotype
- Yemen
- alpha-Thalassemia