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Article

Novel 31.2 kb α0 Deletion in a Palestinian Family with α-Thalassemia.

Hemoglobin - 1 Jan 2015

Brieghel Christian, Birgens Henrik, Frederiksen Henrik, Hertz Jens M, Steenhof Maria, Petersen Jesper

Abstract excerpt

A previously unknown α(0) deletion, designated - -(DANE), was found in three generations of a Danish family of Palestinian origin. Six patients were heterozygous and three patients had deletional Hb H (β4) disease with a compound heterozygosity for the common -α(3.7) (rightward) deletion. Multiplex ligation-dependent probe amplification (MLPA) supplemented by repeated polymerase chain reaction (PCR) amplification...

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Source

Identifiers

PMID: 26114741
DOI: 10.3109/03630269.2015.1054512

Genes

HBA1
HBA2
HBZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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