Article
Alpha thalassaemia in two Spanish families.
European journal of haematology - 1 Feb 1990
Villegas A, Calero F, Vickers M A, Ayyub H, Higgs D R
Abstract excerpt
Two Spanish families with alpha thalassaemia, including 4 individuals with Hb H disease, are described. DNA mapping shows that, in addition to the common alpha thalassaemia determinant (-alpha 3.7), a different and previously unreported allele is present in each family. In one, there is a deletion of 10.5-12 kb of DNA including both alpha genes (--SPAN). In the other, a deletion of more than 100 kb has removed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.