Article
Alpha thalassaemia in two Spanish families.
European journal of haematology - 1 Feb 1990
Villegas A, Calero F, Vickers M A, Ayyub H, Higgs D R
Abstract excerpt
Two Spanish families with alpha thalassaemia, including 4 individuals with Hb H disease, are described. DNA mapping shows that, in addition to the common alpha thalassaemia determinant (-alpha 3.7), a different and previously unreported allele is present in each family. In one, there is a deletio...
Topics
- Alleles
- Chromosome Deletion
- DNA
- England
- Female
- Genotype
- Globins
- Humans
- Male
- Pedigree
- RNA Caps
- Restriction Mapping
- Spain
- Thalassemia