Article
A Novel 31.1 kb α-Thalassemia Deletion (- -MEX3) Found in a Mexican Family.
Hemoglobin - 1 May 2017
Rentería-López Víctor M, Perea-Díaz Francisco J, Rizo-delaTorre Lourdes C, Sánchez-López Josefina Y, Ibarra-Cortés Bertha
Abstract excerpt
α-Thalassemia (α-thal), a genetic disease characterized by microcytosis, hypochromia and anemia, is predominantly caused by deletions of the α-globin genes, HBA2 and HBA1. In this study, we describe a novel 31.1 kb α-thal deletion, - -MEX3 (NC_000016.10: g.151479_182582del), observed in a Mexican family, probably originated from non homologous recombination between two Alu sequences; the 5' Alu element has been...
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