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Article

Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia.

1 Jan 1994

Abstract excerpt

The translocation (6;9) in acute nonlymphocytic leukemia results in the formation of a dek-can fusion gene. In a case of acute undifferentiated leukemia, the oncogene can is fused to a different gene, named set, instead of dek and is assumed to be activated. Transcripts of set encode a putative SET protein with a predicted molecular mass of 32 kDa. We identified SET as a 39-kDa protein by immunoprecipitation with...

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PMID: 8294483
DOI: 10.1016/s0021-9258(17)42162-4

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Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia.PMID 8294483Read ↗

Identification of in vivo phosphorylation sites of SET, a nuclear phosphoprotein encoded by the translocation breakpoint in acute undifferentiated leukemiaSemantic proximity Read ↗

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Activating PAX gene family paralogs to complement PAX5 leukemia driver mutations.Semantic proximity Read ↗

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HRX Leukemic Fusion Proteins Form a Heterocomplex with the Leukemia-associated Protein SET and Protein Phosphatase 2ASemantic proximity Read ↗

Unexpected functional role of the transactivation domain for nuclear import of STAT5Semantic proximity Read ↗

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