Article
Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway.
Molecular and cellular biology - 1 Feb 1994
Hasson M S, Blinder D, Thorner J, Jenness D D
Abstract excerpt
The STE5 gene encodes an essential element of the pheromone response pathway which is known to act either after the G subunit encoded by the STE4 gene or at the same step. Mutations in STE5, designated STE5Hyp, that partially activate the pathway in the absence of pheromone were isolated. One all...
Topics
- Adaptor Proteins, Signal Transducing
- Alleles
- Carrier Proteins
- Crosses, Genetic
- Fungal Proteins
- GTP-Binding Proteins
- Gene Expression Regulation, Fungal
- Genotype
- Hydroxylamine
- Hydroxylamines
- Macromolecular Substances
- Mating Factor
- Mutagenesis
- Mutagens
- Peptides
- Pheromones
- Plasmids
- Protein Kinases