Article
Metabolic role of cytoplasmic isozymes of 5,10-methylenetetrahydrofolate dehydrogenase in Saccharomyces cerevisiae.
Biochemistry - 5 Mar 1996
West M G, Horne D W, Appling D R
Abstract excerpt
Saccharomyces cerevisiae possesses two cytosolic 5,10-methylenetetrahydrofolate (CH2-THF) dehydrogenases that differ in their redox cofactor specificity: an NAD-dependent dehydrogenase encoded by the MTD1 gene and an NADP-dependent activity as part of the trifunctional C1-THF synthase encoded by...
Topics
- Animals
- CHO Cells
- Cricetinae
- Cytosol
- Genotype
- Glycine
- Isoenzymes
- Kinetics
- Liver
- Magnetic Resonance Spectroscopy
- Methylenetetrahydrofolate Dehydrogenase (NADP)
- Models, Biological
- NAD
- NADP
- Phenotype
- Plasmids
- Rats
- Recombinant Proteins