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Article

Toxoplasma gondii: susceptibility and development of resistance to anticoccidial drugs in vitro.

Antimicrobial agents and chemotherapy - 1 Nov 1993

Ricketts A P, Pfefferkorn E R

Abstract excerpt

Anticoccidial drugs were evaluated for activity and for the development of resistance in a model of Toxoplasma gondii growing in human fibroblast cultures. Of 13 anticoccidial drugs tested, 9 had selective antitoxoplasma activity (50% inhibitory concentration, in micrograms per milliliter): decoquinate (0.005), arprinocid-N-oxide (0.015), robenidine (0.03), the aryl triazine CP-25,415 (0.2), toltrazuril (0.4),...

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Identifiers

PMID: 8285619
DOI: 10.1128/AAC.37.11.2358
PMCID: PMC192392

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