Article
Toxoplasma gondii: susceptibility and development of resistance to anticoccidial drugs in vitro.
Antimicrobial agents and chemotherapy - 1 Nov 1993
Ricketts A P, Pfefferkorn E R
Abstract excerpt
Anticoccidial drugs were evaluated for activity and for the development of resistance in a model of Toxoplasma gondii growing in human fibroblast cultures. Of 13 anticoccidial drugs tested, 9 had selective antitoxoplasma activity (50% inhibitory concentration, in micrograms per milliliter): decoq...
Topics
- Animals
- Coccidiostats
- Drug Resistance
- Eimeria tenella
- Fibroblasts
- Humans
- Mutagenesis
- Mutation
- Thymidine
- Toxoplasma