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Article

Organization and evolution of an alpha satellite DNA subset shared by human chromosomes 13 and 21.

Journal of molecular evolution - 1 Nov 1993

Greig G M, Warburton P E, Willard H F

Abstract excerpt

The structure of the alpha satellite DNA higher-order repeat (HOR) unit from a subset shared by human chromosomes 13 and 21 (D13Z1 and D21Z1) has been examined in detail. By using a panel of hybrids possessing either a chromosome 13 or a chromosome 21, different HOR unit genotypes on chromosomes 13 and 21 have been distinguished. We have also determined the basis for a variant HOR unit structure found on...

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PMID: 8283478
DOI: 10.1007/BF00160427

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