Article
Molecular characterization of ovarian tumors in Drosophila.
Mechanisms of development - 1 Aug 1994
Bae E, Cook K R, Geyer P K, Nagoshi R N
Abstract excerpt
Certain female-sterile mutations in Drosophila result in the uncontrolled proliferation of X/X germ cells. It has been proposed that this ovarian tumor phenotype results from the sexual transformation of X/X germ cells to a male identity. We present findings inconsistent with this model. We demon...
Topics
- Animals
- Biomarkers, Tumor
- Cell Differentiation
- Drosophila
- Female
- Gene Expression Regulation, Neoplastic
- Male
- Mutation
- Ovarian Neoplasms
- RNA, Messenger
- X Chromosome