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Article

Molecular characterization of ovarian tumors in Drosophila.

Mechanisms of development - 1 Aug 1994

Bae E, Cook K R, Geyer P K, Nagoshi R N

Abstract excerpt

Certain female-sterile mutations in Drosophila result in the uncontrolled proliferation of X/X germ cells. It has been proposed that this ovarian tumor phenotype results from the sexual transformation of X/X germ cells to a male identity. We present findings inconsistent with this model. We demonstrate that the tumorous cells produced by mutations in the ovarian tumor (otu), Sex-lethal (Sxl) and sans fille (snf)...

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Source

Identifiers

PMID: 7811638
DOI: 10.1016/0925-4773(94)90087-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular characterization of ovarian tumors in Drosophila.PMID 7811638Read ↗

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Chinmo is sufficient to induce male fate in somatic cells of the adult Drosophila ovary.Semantic proximity Read ↗

Effects of Wolbachia infection and ovarian tumor mutations on Sex-lethal germline functioning in Drosophila.Semantic proximity Read ↗

A specific ovarian tumor protein isoform is required for efficient differentiation of germ cells in Drosophila oogenesis.Semantic proximity Read ↗

Induction of female Sex-lethal RNA splicing in male germ cells: implications for Drosophila germline sex determination.Semantic proximity Read ↗

Identification of new X-chromosomal genes required for Drosophila oogenesis and novel roles for fs(1)Yb, brainiac and dunce.Semantic proximity Read ↗

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Genetic and molecular characterization of P element-induced mutations reveals that the Drosophila ovarian tumor gene has maternal activity and a variable null phenotype.Semantic proximity Read ↗

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