Antigenic diversity in Plasmodium falciparum.

Abstract excerpt

There are several mechanisms responsible for the extensive antigenic diversity found in the asexual blood stages of Plasmodium falciparum. Failure to express antigens is a feature of many isolates cultured in vitro but probably is not a major cause of antigenic diversity in vivo. Numerous point mutations occur in allelic forms of asexual blood stage antigens and are assumed to contribute to antigenic diversity...

Topics

• Animals
• Antigenic Variation
• Antigens, Protozoan
• Chromosome Mapping
• Malaria
• Mutation
• Plasmodium falciparum
• Polymorphism, Genetic