Enhancement of recombinant gamma-aminobutyric acid type A receptor currents by chronic activation of cAMP-dependent protein kinase.

Article

Enhancement of recombinant gamma-aminobutyric acid type A receptor currents by chronic activation of cAMP-dependent protein kinase.

Molecular pharmacology - 1 Dec 1993

Angelotti T P, Uhler M D, Macdonald R L

Abstract excerpt

alpha 1, beta 1, and gamma 2S gamma-aminobutyric acid (GABA) type A receptor (GABAR) subunit cDNAs were transiently expressed in derivative cell lines of mouse L929 fibroblasts, which possessed different levels of the catalytic subunit of cAMP-dependent protein kinase (PKA). These cell lines incl...

Topics

Animals
Base Sequence
Cell Line
Enzyme Activation
Membrane Potentials
Mice
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides
Protein Kinases
Receptors, GABA
Recombinant Proteins

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