Article
Frequent occurrence of familial aggregations of high lipoprotein(a) levels associated with small apolipoprotein(a) isoforms.
Human genetics - 1 Dec 1993
Yanagi H, Nakagawa A, Kikuchi S, Tanaka T, Tsuchiya S, Hamaguchi H
Abstract excerpt
School-age children with high lipoprotein(a) [Lp(a)] levels were screened and family studies were conducted to examine the relationship between high Lp(a) levels and apolipoprotein(a) [apo(a)] isoforms in families. All the probands from 17 families had one of the A2 to A12 apo(a) isoforms, which are the smaller apo(a) isoforms of the 25 different isoforms thus far detected. The ratio of subjects with high plasma...
Topics
- Alleles
- Apolipoproteins A
- Child
- Electrophoresis, Polyacrylamide Gel
- Female
- Gene Frequency
- Humans
- Hyperlipoproteinemias
- Immunoenzyme Techniques
- Lipoprotein(a)
- Male