Apolipoprotein(a) phenotypes are reliable biomarkers for familial aggregation of coronary heart disease.

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Article

Apolipoprotein(a) phenotypes are reliable biomarkers for familial aggregation of coronary heart disease.

International journal of molecular medicine - 1 Feb 2004

Peros Emmanouil, Geroldi Diego, D'Angelo Angela, Falcone Colomba, Montagna Lorenza, Carabela Maria, Emanuele Enzo

Abstract excerpt

Lipoprotein(a) [Lp(a)] is an atherogenic and prothrombotic molecule formed by the covalent binding of the highly polymorphic apolipoprotein(a) [apo(a)] to apoprotein B-100 of LDL. High Lp(a) concentrations are a recognized genetic risk factor for coronary heart disease (CHD) and have been shown to be related with a familial clustering of ischemic cardiac events. Nevertheless, the association between...

Topics

Apolipoproteins
Apoprotein(a)
Coronary Disease
Genetic Markers
Genetic Predisposition to Disease
Humans
Lipoprotein(a)
Middle Aged
Protein Isoforms

Source

Open in PubMed

Identifiers

PMID: 14719130

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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