Article
Apolipoprotein(a) phenotypes are reliable biomarkers for familial aggregation of coronary heart disease.
International journal of molecular medicine - 1 Feb 2004
Peros Emmanouil, Geroldi Diego, D'Angelo Angela, Falcone Colomba, Montagna Lorenza, Carabela Maria, Emanuele Enzo
Abstract excerpt
Lipoprotein(a) [Lp(a)] is an atherogenic and prothrombotic molecule formed by the covalent binding of the highly polymorphic apolipoprotein(a) [apo(a)] to apoprotein B-100 of LDL. High Lp(a) concentrations are a recognized genetic risk factor for coronary heart disease (CHD) and have been shown to be related with a familial clustering of ischemic cardiac events. Nevertheless, the association between...
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