Article
A temperature-sensitive cell cycle arrest mutation affecting H1 phosphorylation and nuclear localization of a small heat shock protein in Tetrahymena thermophila.
Experimental cell research - 1 Dec 1993
Thatcher T H, Gorovsky M A
Abstract excerpt
This report describes a temperature-sensitive Tetrahymena thermophila cell cycle arrest mutant that is also deficient in its heat shock response. Mutants incubated at 41 degrees C undergo rapid dephosphorylation of macronuclear histone H1, in contrast to wild-type cells which hyperphosphorylate H...
Topics
- Animals
- Cell Compartmentation
- Cell Cycle
- Electrophoresis, Gel, Two-Dimensional
- Heat-Shock Proteins
- Histones
- Hot Temperature
- Mutation
- Nuclear Proteins
- Phosphorylation
- Protamine Kinase
- Tetrahymena thermophila