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Article

A temperature-sensitive cell cycle arrest mutation affecting H1 phosphorylation and nuclear localization of a small heat shock protein in Tetrahymena thermophila.

Experimental cell research - 1 Dec 1993

Thatcher T H, Gorovsky M A

Abstract excerpt

This report describes a temperature-sensitive Tetrahymena thermophila cell cycle arrest mutant that is also deficient in its heat shock response. Mutants incubated at 41 degrees C undergo rapid dephosphorylation of macronuclear histone H1, in contrast to wild-type cells which hyperphosphorylate H1 under the same conditions. Dephosphorylation is specific to H1 and is associated with a threefold decrease in the...

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Source

Identifiers

PMID: 8262144
DOI: 10.1006/excr.1993.1310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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