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Article

A beta-tubulin mutation selectively uncouples nuclear division and cytokinesis in Tetrahymena thermophila.

Eukaryotic cell - 1 Oct 2004

Smith Joshua J, Yakisich J Sebastian, Kapler Geoffrey M, Cole Eric S, Romero Daniel P

Abstract excerpt

The ciliated protozoan Tetrahymena thermophila contains two distinct nuclei within a single cell-the mitotic micronucleus and the amitotic macronucleus. Although microtubules are required for proper division of both nuclei, macronuclear chromosomes lack centromeres and the role of microtubules in macronuclear division has not been established. Here we describe nuclear division defects in cells expressing a mutant...

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Source

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Identifiers

PMID: 15470250
DOI: 10.1128/EC.3.5.1217-1226.2004
PMCID: PMC522614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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