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Article

Microsatellite polymorphisms at the glucokinase locus: a population association study in Caucasian type 2 diabetic subjects.

Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 1993

Hattersley A T, Saker P J, Cook J T, Stratton I M, Patel P, Permutt M A, Turner R C, Wainscoat J S

Abstract excerpt

Glucokinase has a central role in glucose metabolism in pancreatic beta cells and hepatocytes and is an important candidate gene for Type 2 diabetes. Mutations of the glucokinase gene have been reported in Caucasian pedigrees with maturity-onset diabetes of the young and late-onset Type 2 diabetes. In population studies of American Blacks and Mauritian Creoles an association between alleles of a glucokinase...

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Source

Identifiers

PMID: 8261750
DOI: 10.1111/j.1464-5491.1993.tb00150.x

Genes

GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microsatellite polymorphisms at the glucokinase locus: a population association study in Caucasian type 2 diabetic subjects.PMID 8261750Read ↗

Two microsatellite repeat polymorphisms flanking opposite ends of the human glucokinase gene: use in haplotype analysis of Welsh Caucasians with type 2 (non-insulin-dependent) diabetes mellitus.Semantic proximity Read ↗

A novel heterozygous mutation in the glucokinase gene is responsible for an early-onset mild form of maturity-onset diabetes of the young, type 2.Semantic proximity Read ↗

Screening of mutations and polymorphisms in the glucokinase gene in Czech diabetic and healthy control populations.Semantic proximity Read ↗

Identification of 21 novel glucokinase (GCK) mutations in UK and European Caucasians with maturity-onset diabetes of the young (MODY).Semantic proximity Read ↗

Glucokinase gene polymorphisms: a genetic marker for glucose intolerance in a cohort of elderly Finnish men.Semantic proximity Read ↗

Glucokinase gene in gestational diabetes mellitus: population association study and molecular scanning.Semantic proximity Read ↗

Identification of two new mutations in the glucokinase gene that result in maturity-onset diabetes of the young.Semantic proximity Read ↗

Positive association in the absence of linkage suggests a minor role for the glucokinase gene in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus amongst south Indians.Semantic proximity Read ↗

Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase.Semantic proximity Read ↗

Linkage of type 2 diabetes to the glucokinase gene.Semantic proximity Read ↗

Glucokinase gene variants in subjects with late-onset NIDDM and impaired glucose tolerance.Semantic proximity Read ↗

The population association of glucokinase gene with type 2 (noninsulin-dependent) diabetes mellitus in Chinese.Semantic proximity Read ↗

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