Article
Identification of viral membrane proteins required for cell fusion and viral dissemination that are modified during vaccinia virus persistence.
Virology - 1 Jan 1994
Ortiz M A, Paez E
Abstract excerpt
Wild-type vaccinia virus WR strain forms non-fusogenic (F-) large plaques and is hemagglutinin positive (HA+) under normal conditions of virus infection. We have analyzed a collection of spontaneous, highly attenuated mutants of vaccinia virus isolated from persistently infected Friend erythroleu...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Fusion
- Cytopathogenic Effect, Viral
- Friend murine leukemia virus
- Hemagglutinins, Viral
- Hydrogen-Ion Concentration
- Leukemia, Erythroblastic, Acute
- Molecular Sequence Data
- Mutation
- Recombination, Genetic
- Restriction Mapping
- Sequence Deletion
- Tumor Cells, Cultured
- Vaccinia virus
- Viral Fusion Proteins
- Viral Matrix Proteins