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Article

In vitro activity of penciclovir against clinical isolates of acyclovir-resistant and foscarnet-resistant herpes simplex virus.

Antimicrobial agents and chemotherapy - 1 Oct 1993

Safrin S, Phan L

Abstract excerpt

We tested 23 clinical isolates of acyclovir-susceptible, acyclovir-resistant, and foscarnet-resistant herpes simplex virus for susceptibility to penciclovir. Isolates showed cross-resistance to penciclovir and acyclovir, but penciclovir retained a relative activity against foscarnet-resistant isolates. Its clinical utility for the treatment of resistant herpes simplex virus infections remains to be studied.

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Identifiers

PMID: 8257152
DOI: 10.1128/AAC.37.10.2241
PMCID: PMC192259

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Source receipt: pubmed, retrieved 7 Sept 2026.

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