Article
Non-allelic heterogeneity of familial adenomatous polyposis.
American journal of medical genetics - 15 Sept 1993
Tops C M, van der Klift H M, van der Luijt R B, Griffioen G, Taal B G, Vasen H F, Khan P M
Abstract excerpt
Linkage studies on familial adenomatous polyposis (FAP) reported so far suggest that FAP is a genetically homogeneous disease. Recently, we found that the putative gene for Turcot syndrome, an apparently autosomal recessive clinical variant of FAP, is not allelic to FAP. Here we describe another family, segregating for an autosomal dominant disease clinically indistinguishable from FAP but genetically not linked...
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