The biology of normal and neoplastic stem cells in CML.

doi:10.3109/10428199309047894

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Article

The biology of normal and neoplastic stem cells in CML.

Leukemia & lymphoma - 1 Jan 1993

Eaves C, Udomsakdi C, Cashman J, Barnett M, Eaves A

Abstract excerpt

Chronic myeloid leukemia (CML) has long served as a prototype malignancy for basic as well as clinical studies aimed at developing curative cancer treatment protocols. Well established features of chronic phase CML are its origin in a pluripotent stem cell, a now well defined molecular genetic ba...

Topics

Blood Cells
Bone Marrow
Cell Differentiation
Cell Division
Chemokine CCL4
Clone Cells
Cytokines
Fusion Proteins, bcr-abl
Hematopoietic Stem Cells
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Macrophage Inflammatory Proteins
Monokines
Neoplastic Stem Cells
Phenotype
Transforming Growth Factor beta
Tumor Cells, Cultured

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PMID: 8251904
DOI: 10.3109/10428199309047894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8251904-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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