The disulfide bridges of the immunoglobulin-like domains of Fc gamma RIIIB are essential for efficient expression and biological activity.

doi:10.1007/BF01025046

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Article

The disulfide bridges of the immunoglobulin-like domains of Fc gamma RIIIB are essential for efficient expression and biological activity.

Journal of protein chemistry - 1 Aug 1993

Enenkel B, Frey J

Abstract excerpt

The immunoglobulin G receptor Fc gamma RIIIB belongs to the immunoglobulin superfamily as two extracellular domains show homology to the immunoglobulin domains. Since some residues in these domains, such as the two cysteines, are supposed to form an intrachain disulfide bridge are so commonly con...

Topics

Animals
Base Sequence
Cell Line
Cricetinae
Disulfides
Molecular Sequence Data
Mutation
Receptors, IgG
Structure-Activity Relationship

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